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Chronic Myeloid Leukaemia

Overview

Chronic myeloid leukaemia is often asymptomatic during the early phase of the disease. Patients may be quite young. High white cell counts are noted with increase in both mature and immature white cells. Platelet count is also at a high level. Spleen is usually enlarged.

Symptoms and Diagnosis

  • Full blood counts
  • Bone marrow biopsy
  • Cytogenetic study showing “Philadelphia Chromosome”
  • FISH analysis or polymerase chain reaction to detect bcr-abl translocation

Procedures and Treatments

Treatments

  • Tyrosine kinase inhibitors (TKI) , e.g. Imatinib, Nilotinib or Dasatinib
  • Long-term therapy is required
  • Genetic test monitoring is necessary 


Prognosis

  • If not properly treated, the disease transforms to refractory acute leukaemia with an average period of 3 years
  • Most patients respond very well to tyrosine kinase inhibitors and have a long survival period
     

Contact Us

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Happy Valley

Address:
3/F, Li Shu Fan Block,
Hong Kong Sanatorium & Hospital,
2 Village Road, Happy Valley, Hong Kong
Service hours:
Monday to Friday: 9:00 am - 5:00 pm
Saturday: 9:00 am - 1:00 pm
Closed on Sundays and Public Holidays
Consultation by Appointment

Tel.:
(852) 2835 8877
Email:
[javascript protected email address]
Fax:
(852) 2892 7520
WhatsApp:
(852) 9151 8306
(For non-emergency cases)
Please provide name and contact number in text message in WhatsApp. Our Centre will contact you by phone to confirm. Do not send voice messages or graphics.
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Island East

Address:
11/F, HKSH Eastern Building,
3 Tung Wong Road, Shau Kei Wan, Hong Kong
Service hours:
Monday to Friday: 9:00 am - 5:00 pm
Saturday: 9:00 am - 1:00 pm
Closed on Sundays and Public Holidays
Consultation by Appointment

Tel.:
(852) 2917 1200
Email:
[javascript protected email address]
Fax:
(852) 2892 7599
WhatsApp:
(852) 2917 1200
(For non-emergency cases)
Please provide name and contact number in text message in WhatsApp. Our Centre will contact you by phone to confirm. Do not send voice messages or graphics.
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Island East

Address:
11/F, HKSH Eastern Building,
3 Tung Wong Road, Shau Kei Wan, Hong Kong
Service hours:
Monday to Friday: 9:00 am - 5:00 pm
Saturday: 9:00 am - 1:00 pm
Closed on Sundays and Public Holidays
Consultation by Appointment

Tel.:
(852) 2917 1200
Email:
[javascript protected email address]
Fax:
(852) 2892 7599
WhatsApp:
(852) 2917 1200
(For non-emergency cases)
Please provide name and contact number in text message in WhatsApp. Our Centre will contact you by phone to confirm. Do not send voice messages or graphics.